### 大分子链上悬挂功能基团尺寸对于糖淀粉螺旋内穴中受物反应性的影响

1. 中国科学院上海有机化学研究所
• 出版日期:1989-08-15 发布日期:1989-08-15

### The effects of functional group size in macromolecular chain on the reactivity of substrates in helical cavity of amylose

HUI YONGZHENG;ZOU WEI

• Online:1989-08-15 Published:1989-08-15

The different effects of some amylose derivatives on the hydrolysis of N-dodecyl-2-chloropyridinium iodide (I) and p-nitrophenyl laurate (II) have been studied. Either aminoethylamylose (AEA) or imidazole catalyzes the hydrolysis of I, but carboxymethylhistaminoacylmethylamylose (CHA) inhibits the reaction. This result could be attributed to the size differential between amino and imidazole groups, in same way, carboxymethyldiaminoethylacylmethylamylose (CAA) catalyzes the hydrolysis of a neutral substrate II much efficiently than CHA. From the study of degree of substitution in CHA on hydrolysis of N-dodecyl-3-acetyloxypyridinium iodide, a same conclusion from enzyme catalysis that a loose complex between host and substrate possesses higher catalytic efficiency can be derived based on this model system.