Acta Chimica Sinica ›› 2014, Vol. 72 ›› Issue (5): 552-556.DOI: 10.6023/A14030155 Previous Articles     Next Articles

Communication

Pd/MgO:一种基于芳香羧酸脱羧与卤代芳烃的交叉偶联反应体系的可循环的多相催化剂

李召好b, 陈静a, 苏伟平a, 洪茂椿a   

  1. a 中国科学院煤制乙二醇及相关技术重点实验室 结构化学国家重点实验室 中国科学院福建物质结构研究所 福州 350002;
    b 洛阳师范学院化学化工学院 471022
  • 收稿日期:2014-03-11 出版日期:2014-05-14 发布日期:2014-04-13
  • 通讯作者: 苏伟平 E-mail:wpsu@fjirsm.ac.cn
  • 基金资助:

    项目受973(Nos. 2011CB932404,2011CBA00501)、国家自然科学基金(No. 21103192)和中科院重点项目资助.

Pd/MgO:A Recyclable, Ligand-free Heterogeneous Catalyst for Decarboxylative Cross-Coupling of Arene Carboxylic Acids with Aryl Halides

Li Zhaohaob, Chen Jinga, Su Weipinga, Hong Maochuna   

  1. a Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002;
    b College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022
  • Received:2014-03-11 Online:2014-05-14 Published:2014-04-13
  • Supported by:

    Project supported by the 973 Program (Nos. 2011CB932404, 2011CBA00501), the National Natural Science Foundation of China (No. 21103192) and the Key Project from Chinese Academy of Sciences.

Decarboxylative coupling of arene carboxylic acids with aryl halides is achieved by using a ligand-free Pd/MgO (0.5 mol% Pd) heterogeneous catalyst system. Both electron-rich and electron-deficient arene carboxylic acids can be used as aryl sources to couple a variety of aryl bromides, even aryl chlorides in moderate-to-excellent yields. The establishment of heterogeneous catalysis for the decarboxylative cross-coupling along with the reusability of the heterogeneous catalyst should facilitate the practical application of this transformation in organic synthesis.

Key words: palladium, decarboxylation, carboxylic acid, cross-coupling, heterogeneous catalysis