Acta Chimica Sinica ›› 2021, Vol. 79 ›› Issue (5): 658-662.DOI: 10.6023/A21010005 Previous Articles     Next Articles



杨妲a, 张龙力a,*(), 刘欢a,*(), 杨朝合b   

  1. a 中国石油大学(华东)理学院 青岛 266580
    b 中国石油大学(华东)重质油国家重点实验室 青岛 266580
  • 投稿日期:2021-01-08 发布日期:2021-02-23
  • 通讯作者: 张龙力, 刘欢
  • 基金资助:
    项目受中国博士后科学基金(2019M662460); 自主创新科研计划项目(20CX06033A)

Co-catalysis over Bi-functional Ligand Based Ir-catalyst for Tandem Hydroformylation-acetalization Reaction

Da Yanga, Longli Zhanga,*(), Huan Liua,*(), Chaohe Yangb   

  1. a College of Science, China University of Petroleum (East China), Qingdao 266580, China
    b State Key Laboratory of Heavy Oil Processing, China University of Petroleum (East China), Qingdao 266580, China
  • Received:2021-01-08 Published:2021-02-23
  • Contact: Longli Zhang, Huan Liu
  • About author:
  • Supported by:
    China Postdoctoral Science Foundation(2019M662460); Fundamental Research Funds for the Central Universities(20CX06033A)

The ionic bi-functional ligands of L2 and L3 in combination of a phosphine with a Lewis acidic phosphonium were synthesized through selective quaternized by MeI at the one P-position of the bi-dentate ligands. Due to the separation by the rigid ring, the incorporated -PPh2 and the Lewis acidic phosphonium were well retained without quenching problem. In the bi-functional ligands, the phosphine group could coordinate with transition metals, the phosphonium group could present Lewis acidic. The Ir(I)-complex modified by the “phosphino-phosphonium” bi-functional ligand ( L2) was used to catalyze the tandem hydroformylation-acetalization of olefins. Under the optimized conditions ([Ir(COD)Cl]2 0.025 mmol, L2 0.025 mmol, 1-octene 5.0 mmol, methanol 5.0 mL, N-methyl pyrrolidone 2.0 mL, VCO/VH2=4∶1 4.0 MPa, temperature 120 ℃, reaction time 8 h), the conversion of 1-octene was 97% with the selectivity of acetals up to 86%, which was analyzed by GC and GC-MS. In this system, the activity of Ir catalyst was better than that of Rh catalyst at same conditions. It was found thatL2-modified [Ir(COD)Cl]2 could also efficiently accelerate this tandem reaction, which proved more effective than the ligands lacking phosphonium or the mechanical mixtures of the individual functional groups independently. It was believed that, in L2, the phosphonium not only acted as a Lewis acid organocatalyst to drive the sequential acetalization of aldehydes, but also contributed to the synergetic catalysis for the preceding hydroformylation through stabilizing the Ir-acyl intermediate with the phosphine cooperatively. The L2-[Ir(COD)Cl]2 system is also generally applied to the tandem hydroformylation-acetalization reaction of a wide range of olefins in different alcohols, give the yields of products in the range of 45%~87%. Advantageously, as an ionic ligand with high polarity, L2-based Ir(I)-catalyst could be precipitated by n-hexane upon completion to fulfil the recovery and recycling uses of transition metal catalysts.

Key words: hydroformylation, acetalization, tandem reaction, bi-functional ligand, Ir-catalyst