Acta Chimica Sinica ›› 1964, Vol. 30 ›› Issue (2): 183-192. Previous Articles     Next Articles

1, 2, 4-三嗪类化合物的研究Ⅲ.3, 5-取代-1, 2, 4-三嗪-6-羧酸及其衍生物

王序, 蔡孟深, 何颖镛, 李际和   

  1. 北京医学院药学系
  • 收稿日期:1963-06-22 出版日期:1964-04-15 发布日期:2013-06-03

CHEMISTRY OF 1, 2, 4-TRIAZINES Ⅲ. 3,5-DISUBSTITUTED-1, 2, 4-TRIAZINE-6-CARBOXYLIC ACIDS AND THEIR DERIVATIVES

WANG HSIU(HSIU WANG), TSAI MENG-SHENG, HO YING-YUNG AND LI CHI-HO   

  1. Department of Pharmacy, Peking Medical College
  • Received:1963-06-22 Online:1964-04-15 Published:2013-06-03

The preparations and properties of some 3,5-disubstituted-1,2,4-triazine-6-carboxylic acids and their derivatives were reported.Ethyl 3-thiono-5-oxo- or 3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxylate reacted with aqueous ammonia or with hydrazine hydrate to give stable ammonium salts of the corresponding amides or the hydrazine salts of the corresponding hydrazides.But 3-thiono-5-oxo- or 3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazines and their 6-methyl derivatives could not form salts with ammonia.