Acta Chimica Sinica ›› 1980, Vol. 38 ›› Issue (4): 361-370. Previous Articles     Next Articles

翼梗五味子的研究 Ⅱ.翼梗五味子酯和翼梗五味子酸的结构

刘嘉森, 黄梅芬, 高耀良   

  1. 中国科学院上海药物研究所
  • 收稿日期:1978-08-22 出版日期:1980-07-15 发布日期:2013-06-03

STUDIES ON THE CONSTITUENTS OF SCHISANDRA HENRYI CLARKE Ⅱ. THE STRUCTURES OF SCHISANHENRIN AND SCHISANHENRIC ACID

LIU JIA-SEN, HUANG MEI-FEN, GAO YAO-LIANG   

  1. Shanghai Institute of Materia Medica, Academia Sinica
  • Received:1978-08-22 Online:1980-07-15 Published:2013-06-03

Four crystalline compounds have boon isolated from the fruits of Schisandra henryi Clarke (Magnoliaceae) besides schisanhenol.Two of them have been identified as the known schisantherin B (1) and kadsuric acid (3),but the other two are new compounds, namely schisanhenrin (2) and schisanhenric acid (4).The structure of schisanhenrin (2, C28H34O9, m.p.88℃, [a]D23-27° in CHCl3) has been established as C7(R)-schisantherin B and its absolute configuration as biphenyl(S),C6(S),C7(R),C8 (S),based upon the comparison of its spectra with that of schisantherin B, the results of determination of nuclear Overhauser effect (NOE)(Tab.1) and the fact of formation of cyclic sulfite ester (2b) by reaction of 2a with thionyl chloride.