Acta Chimica Sinica ›› 1993, Vol. 51 ›› Issue (6): 594-601. Previous Articles     Next Articles

Original Articles

生物小分子的电分析化学研究 Ⅱ.鸟嘌呤、腺嘌呤和次黄嘌呤在粗热解石墨电极上的分子定向和表面相互作用

朱世民;瞿文川;陈洪渊   

  1. 南京大学化学系
  • 出版日期:1993-06-15 发布日期:1993-06-15

Study on electroanalytical chemistry of small biological molecules. Ⅱ.molecular orientation and surface interaction of guanine,adenine and hypoxanthine on rough pyrolytic graphite electrode

ZHU SHIMIN;QU WENCHUAN;CHEN HONGYUAN   

  • Online:1993-06-15 Published:1993-06-15

The reactivity of guanine, adenine and hypoxanthine on electrodes made with different materials is discussed. The rough pyrolytic graphite electrode (RPGE) was selected for the electrochem. study. The experiment data indicate that the electrode process is controlled by adsorption and the probes, guanine, adenine and hypoxanthine as mono-mol. layer are adsorbed toward the electrode surface of RPGE in a perpendicular orientation with the H group at C(2)-NH2 position for guanine, C(6)-NH2 position for adenine and N(1)-H position for hypoxanthine. Adsorbed mols. have a repulsive interaction at either surface. The equilibrium constants of adsorption for guanine, adenine and hypoxanthine are about 3.34 x 105, 4.38 x 105 and 4.13 x 105 resp., and the energies of adsorption at RPGE are about 31.5, 32.1, and 32.0 kJ/mol resp., which indicate that guanine, adenine and hypoxanthine all have a moderate to strong phys. adsorption on RPGE.

Key words: GUANINE, ELECTROCHEMICAL ANALYSIS, GRAPHITE, ADENINE, INTERACTIONS, ELECTRODE REACTION, SURFACES ADSORPTION, HYPOXANTHINE, SELECTIVE PARAFFIN OXIDATION, FUEL CELL

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