Acta Chimica Sinica ›› 1993, Vol. 51 ›› Issue (6): 602-606. Previous Articles     Next Articles

Original Articles

双环笼状磷酸酯衍生物的研究Ⅵ:4-取代-2,6,7-三氧杂-1-磷杂双环[2.2.2]辛烷的反应研究

李玉桂;包建春   

  1. 南开大学元素有机化学研究所
  • 出版日期:1993-06-15 发布日期:1993-06-15

Study of caged bicyclic phosphate derivatives.Ⅵ.study on the reaction of 4-substituted-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane

LI YUGUI;BAO JIANCHUN   

  • Online:1993-06-15 Published:1993-06-15

Compared with straight chain phosphites, caged bicyclic phosphites have great differences in nucleophilic reactions due to the tension and high steric hindrance caused by the caged bicyclic structure. The reactions of compound I with sulfuryl chloride, chlorine, bromine, and phosphorus pentachloride was studied. I undergoes the reactions which are similar to Arbuzov reaction to yield the same stereo-conformation ring opening compounds The thiophosphorylation reaction of bicyclic phosphite II was studied and the result shows that 4-N,N-dimethylamino-pyridine is an effective catalyst in the reaction.

Key words: REACTION MECHANISM, CATALYST, SUBSTITUTION REACTION, OXYGEN HETEROCYCLICS, OCTANE P, PHOSPHORIC ACID ESTER, STERIC EFFECT, PHOSPHOROUS HETEROCYCLIC COMPOUNDS, NUCLEOPHILIC REACTION, TENSION

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