Acta Chimica Sinica ›› 1994, Vol. 52 ›› Issue (5): 506-510. Previous Articles     Next Articles

Original Articles

分子内反应与分子内催化III. 溶剂效应对2-(2'-苯并咪唑基)乙 酸乙酯及3- (2'-苯并咪唑基)丙酸乙酯碱性水解的影响

夏道宏;夏炽中   

  1. 石油大学化学工程系.(257062);山西大学分子科学研究所.太原(030006)
  • 出版日期:1994-05-15 发布日期:1994-05-15

Intramolecular reaction and intramolecular catalysis III. Solvent effects on the alkaline hydrolysis of ethyl 2-(2'-benzimidazolyl) acetate and ethyl 3-(2'-benzimidazolyl) propionate

Xia Daohong;Xia Chizhong   

  1. Univ Petr, Dept Chem Engn.Dongying(257062);Shanxi Univ., Inst of Mol Sci.Taiyuan(030006)
  • Online:1994-05-15 Published:1994-05-15

The alkaline hydrolysis kinetics of ethyl 2-(2'-benzimidazolyl) acetate and ethyl 3-(2'-benzimidazolyl) propionate have been measured in DMSO-water, 1, 4-dioxane-water mixed solvents, with the increase of DMSO volume content in the DMSO-water mixture, the observed hydrolysis rate constants of these two esters describe an irregular bell-shape curve respectively. The experimental results conform well to the proposed mechanism of the esters hydrolysis including both the intermolecular specific base catalysis of hydroxide ion and the intramolecular general base catalysis of benzimidazolyl group.

Key words: ETHYL PROPIONATE, BENZIMIDAZOLE, ETHYL ACETATE, SOLVENT EFFECT, INTERNAL MOLECULAR REACTION, ESTERS, HYROLYSIS

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