Acta Chimica Sinica ›› 2004, Vol. 62 ›› Issue (1): 78-82. Previous Articles     Next Articles

麦迪霉素-H2O2缔合/平行催化氢波的研究及其应用

宋俊峰, 李宁, 徐茂田   

  1. 西北大学分析科学研究所, 西安, 710069
  • 收稿日期:2003-02-28 修回日期:2003-08-18 出版日期:2004-01-14 发布日期:2014-01-26
  • 通讯作者: 宋俊峰 E-mail::E-mail:songjunf@nwu.edu.cn
  • 基金资助:
    国家自然科学基金(No.29875017)和陕西省自然科学基金(No.2002B01)资助项目.

Study on Association/Parallel Catalytic Hydrogen Wave in Midecamycin-Hydrogen Peroxide System and Its Application

SONG Jun-Feng, LI Ning, XU Mao-Tian   

  1. Institute of Analytical Science, Northwest University, Xi'an 710069
  • Received:2003-02-28 Revised:2003-08-18 Online:2004-01-14 Published:2014-01-26

A new type of polarographic catalytic wave of organic compound, termed as association/parallel catalytic hydrogen wave, has been reported. The association/parallel catalytic hydrogen wave with such characters as the negative shift of the peak potential and the great increase of the peak current in midecamycin-hydrogen peroxide system was studied. Here hydrogen peroxide as ligand formed an association complex with protonated midecamycin, which caused the peak potential of the catalytic hydrogen wave of midecamycin to shift negatively. Additionally, the great increase of the peak current was due to the further catalysis of the catalytic hydrogen wave by hydroxyl radical produced in the reduction of hydrogen peroxide at electrode. It was determined that the association ratio was 1:1 and the apparent association constant was 7.18. In 0.15 mol·L-1 KH2PO4-NaOH (pH 7.4)-0.02 mol·L-1 H2O2 supporting electrolyte, the second-order derivative peak current of the association/parallel catalytic hydrogen wave with peak potential -1.59 V (vs. SCE) was proportional to the midecamycin concentration in the range of 2.0×10-8~1.0×10-5 mol·L-1. The detection limit was 6×10-9 mol·L-1. The association/parallel catalytic hydrogen wave was two orders in magnitude higher than that of the corresponding catalytic hydrogen wave in analytical sensitivity.

Key words: midecamycin, hydrogen peroxide, association/parallel catalytic hydrogen wave