Acta Chimica Sinica ›› 2010, Vol. 68 ›› Issue (03): 246-250. Previous Articles     Next Articles

Full Papers

烟酸分子印迹复合膜的制备及其分离性能研究

邱增英,钟世安   

  1. (中南大学化学化工学院 长沙 410083)
  • 收稿日期:2009-06-10 修回日期:2009-08-14 出版日期:2010-02-14 发布日期:2010-02-20
  • 通讯作者: 钟世安 E-mail:zhongshian@yahoo.com.cn
  • 基金资助:

    湖南省自然科学基金(06JJ4117)

Preparation and Separation Properties of Molecularly Imprinted Composite Membranes with Nicotinic Acid as Template

Qiu Zengying Zhong Shian*   

  1. (College of Chemistry and Chemical Engineering, Central South University, Changsha 410083)
  • Received:2009-06-10 Revised:2009-08-14 Online:2010-02-14 Published:2010-02-20
  • Contact: zhong shi-an E-mail:zhongshian@yahoo.com.cn

Nicotinic acid molecularly imprinted composite membranes were developed using surface modified polymerization by UV irradiation in the presence of nicotinic acid as template, followed by a deposition of molecularly imprinted polymer layer on the surface of polyvinylidene fluoride microfiltration membranes. Scanning electron micrography (SEM) was used to visualize the surface structure of the imprinted composite membranes. Scatchard analysis shows that equivalent binding sites are formed in the molecularly imprinted composite membranes in the range of investigative concentrations, and the dissociation constant (Kd) of binding sites is 5.55×10-2 mmol•L-1. The binding and permeation experiment for substrates indicates that the molecularly imprinted composite membranes exhibit preferable binding performances for nicotinic acid, and the combining quantity is 6.10 μmol•g-1. Compared with nicotinamide with a similar structure to nicotinic acid, the molecularly imprinted composite membranes show a good selectivity and intense recognition of the template molecule.

Key words: molecularly imprinted technology, imprinted composite membrane, Scatchard analysis, permeation, nicotinic acid

CLC Number: