Acta Chimica Sinica ›› 2006, Vol. 64 ›› Issue (1): 17-21. Previous Articles     Next Articles

焦脱镁叶绿酸-a作为光活化农药的光活化机理研究

吴铁一1,3,屠铁城1,赵红卫1,陈志龙2,姚思德*,1   

  1. (1中国科学院上海应用物理研究所 上海 201800)
    (2中国人民解放军第二军医大学海军医学系 上海 200433)
    (3北京健之素医药科技有限公司 北京 102209)
  • 收稿日期:2005-04-18 修回日期:2005-09-12 出版日期:2006-01-14 发布日期:2006-01-14
  • 通讯作者: 姚思德

Study on the Photoactivated Mechanism of a Kind of Photoactivated Pesticide, Pyrophaeophorbide-a

WU Tie-Yi1,3, TU Tie-Cheng1, ZHAO Hong-Wei1, CHEN Zhi-Long2, YAO Si-De*,1   

  1. (1 Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800)
    (2 Faculty of Naval Medicine, Second Military Medical University, Shanghai 200433)
    (3 Beijing Health Essence Medical Science Technology Co., Ltd, Beijing 102209)
  • Received:2005-04-18 Revised:2005-09-12 Online:2006-01-14 Published:2006-01-14
  • Contact: YAO Si-De

Possibility of pyrophaeophorbide-a to be a kind of photoactivated pesticide was presented. Its photoactivated mechanism was studied by use of time-resolved laser flash photolysis and spin trapped EPR technique. It is found that Type II path (singlet oxygen) exists. And the interaction between singlet oxygen and three kinds of biological molecules (DNA, linoleic acid and L-tryptophan) was also studied.

Key words: pyrophaeophorbide-a, photoactivated pesticide, singlet oxygen, electron paramagnetic resonance