有机化学 ›› 2014, Vol. 34 ›› Issue (1): 54-64.DOI: 10.6023/cjoc201307005 上一篇    下一篇

综述与进展

焦磷酸酯合成的研究进展

侯淑华, 曲忠国, 汤立军   

  1. 渤海大学化学化工学院 辽宁省功能化合物的合成与应用重点实验室 锦州 121013
  • 收稿日期:2013-07-03 修回日期:2013-08-11 出版日期:2014-01-25 发布日期:2013-09-25
  • 通讯作者: 侯淑华 E-mail:shyspa0812@163.com

Advances in the Synthesis of Organic Pyrophosphate

Hou Shuhua, Qu Zhongguo, Tang Lijun   

  1. Department of Chemistry, Liaoning Key Laboratory for the Synthesis and Application of Functional Compounds, Bohai University, Jinzhou 121013
  • Received:2013-07-03 Revised:2013-08-11 Online:2014-01-25 Published:2013-09-25

综述了焦磷酸酯类化合物的合成方法研究进展,分别按照不同的活化方法进行了阐述,包括二环己基碳二亚胺(DCC),NN-羰基二咪唑(CDI),DCC/吗啉/MnCl2/MgSO4,DCC/吗啉/1H-四唑,PPh3/(PyS)2/N-甲基咪唑,磷酰氯二苯酯(DPCP),三氟乙酸酐(TFAA)/N-甲基咪唑,并对部分反应机理进行了讨论.

关键词: 焦磷酸酯, 合成, 进展

The recent advances in the synthesis of organic pyrophosphate are reviewed, based on the coupling methods including dicyclohexylcarbodiimide (DCC), N,N'-carbonyldiimidazole (CDI), DCC/morpholine/MnCl2/MgSO4, DCC/ morpholine/1H-tetrazole, PPh3/(PyS)2/N-methylimidazole, diphenyl phosphorochloridate (DPCP), trifluoroacetic anhydride/N-methylimidazole. Mechanism of some reactions is also discussed.

Key words: organic pyrophosphate, synthesis, advances