有机化学 ›› 2016, Vol. 36 ›› Issue (1): 130-136.DOI: 10.6023/cjoc201507013 上一篇    下一篇

研究论文

磁性纳米粒子负载亚胺吡啶钯催化Suzuki反应研究

张强, 李继航, 赵鑫   

  1. 苏州科技学院化学生物与材料工程学院 苏州 215009
  • 收稿日期:2015-07-16 修回日期:2015-09-22 出版日期:2016-01-25 发布日期:2015-09-30
  • 通讯作者: 张强 E-mail:zhangqiang005@gmail.com
  • 基金资助:

    江苏省自然科学基金(No. BK20150282)和苏州科技学院科研基金(No. XKQ201417)资助项目.

Magnetic Nanoparticle Supported Imino-pyridine Palladium Catalyzed Suzuki Reactions

Zhang Qiang, Li Jihang, Zhao Xin   

  1. School of Chemistry Biology and Material Engineering, Suzhou University of Science and Technology, Suzhou 215009
  • Received:2015-07-16 Revised:2015-09-22 Online:2016-01-25 Published:2015-09-30
  • Supported by:

    Project supported by the Natural Science Foundation of Jiangsu Province (No. BK20150282) and the Scientific Research Foundation of Suzhou University of Science and Technology (No. XKQ201417).

以硅胶包裹的纳米四氧化三铁为磁性载体, 经硅烷化亚胺吡啶配体化学改性后与钯盐配位, 制备一种新型磁性钯催化剂, 采用元素分析、红外光谱、透射电镜、X射线光电子能谱以及电感耦合等离子发射光谱等手段对催化剂进行了表征, 并将其应用于水溶液相Suzuki反应. 结果表明, 这种新颖的磁性纳米粒子负载钯催化剂在空气氛围和较低的钯催化量下即可有效地催化多种溴代芳烃和芳基硼酸的Suzuki反应, 产率达83%~98%. 此外, 该催化剂通过磁分离来高效回收, 可循环使用5次且催化活性无明显下降.

关键词: 磁性纳米粒子, 钯催化剂, Suzuki反应, 席夫碱

A new magnetic nanoparticle supported palladium catalyst was successfully prepared by attaching palladium acetates to imino-pyridine ligand functionalized silica-coated nano-Fe3O4. The as-prepared catalyst was characterized by element analysis, FTIR, TEM, XPS and ICP-AES. It was found to be an efficient catalyst for Suzuki reactions in aqueous medium. And the reactions of various aryl bromides with arylboronic acids could be carried out under air and low Pd loading conditions with 83%~98% yields. Moreover, the catalyst could be easily recovered by magnetic separation and reused five times without a significant loss of catalytic activity.

Key words: magnetic nanoparticle, palladium catalyst, Suzuki reaction, Schiff base