有机化学 ›› 2016, Vol. 36 ›› Issue (1): 137-142.DOI: 10.6023/cjoc201507020 上一篇    下一篇

研究论文

二甲基乙酰胺高效促进由醇制备氯代烃

郑大贵, 周安西, 祝显虹, 郑洪富, 孙向前   

  1. 上饶师范学院 江西省普通高校应用有机化学重点实验室 上饶 334001
  • 收稿日期:2015-07-20 修回日期:2015-09-15 出版日期:2016-01-25 发布日期:2015-09-25
  • 通讯作者: 郑大贵 E-mail:daguizheng@163.com
  • 基金资助:

    信江英才866工程领军人才培养计划(No. 2013-37)资助项目.

An Efficient Dimethylacetamide-Promoted Conversion ofAlcohols to Alkyl Chlorides

Zheng Dagui, Zhou Anxi, Zhu Xianhong, Zheng Hongfu, Sun Xiangqian   

  1. Key Laboratory of Applied Organic Chemistry, Higher Institutions of Jiangxi Province, Shangrao Normal University, Shangrao 334001
  • Received:2015-07-20 Revised:2015-09-15 Online:2016-01-25 Published:2015-09-25
  • Supported by:

    Project supported by the Xinjiang 866 Project of Excellence Talent (No. 2013-37).

在二甲基乙酰胺(DMAc)中, 醇与SOCl2在室温下反应, 高产率地得到相应的氯代烃. 为氯代烃的合成提供了一种新的方法.

关键词: 二甲基乙酰胺, 醇, 氯代烃, 合成

A simple and efficient method for the conversion of alcohols to the corresponding alkyl chlorides by using dimethylacetamide (DMAc) as a promoter was developed. It provides a new and practical protocol for the synthesis of alkyl chlorides.

Key words: dimethylacetamide, alcohol, alkyl chlorides, synthesis