有机化学 ›› 2017, Vol. 37 ›› Issue (2): 314-334.DOI: 10.6023/cjoc201608009 上一篇    下一篇

综述与进展

铁催化碳-碳偶联反应研究进展

李娟华a, 刘昆明a, 段新方b, 刘晋彪a   

  1. a 江西理工大学冶金与化学工程学院 赣州 341000;
    b 北京师范大学化学学院 北京 100875
  • 收稿日期:2016-08-16 修回日期:2016-09-22 出版日期:2017-02-25 发布日期:2016-10-18
  • 通讯作者: 刘昆明 E-mail:liukunminglkm@sina.com
  • 基金资助:

    国家自然科学基金(Nos.21372031,21502075)、江西理工大学博士启动经费资助项目.

Recent Progress in Iron Catalyzed C-C Coupling Reactions

Li Juanhuaa, Liu Kunminga, Duan Xinfangb, Liu Jinbiaoa   

  1. a School of Metallurgy and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000;
    b Department of Chemistry, Beijing Normal University, Beijing 100875
  • Received:2016-08-16 Revised:2016-09-22 Online:2017-02-25 Published:2016-10-18
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21372031, 21502075) and the Doctoral Scientific Research Foundation of Jiangxi University of Science and Technology.

过渡金属催化的偶联反应是构建碳-碳键的重要手段.Fe具有储量丰富、价廉低毒、价态多样的特点,是一种理想的催化剂.随着人们对绿色、高效、高选择性反应的重视,铁催化的偶联反应研究日益增多.特别是近10年来,出现许多新的催化体系,催生出多种反应类型,如氧化偶联、还原偶联和C-H直接官能团化.根据偶联反应的类型,综述了近年来铁催化碳-碳偶联反应的研究进展.主要介绍各反应的特点、反应机理和应用,并展望其发展前景.

关键词: 铁催化, 碳-碳偶联反应, 有机合成

Transition-metal-catalyzed coupling reactions play an important role in construct C-C bond. As one of the most abundant metal in the earth's crust, along with its inexpensive price, relatively low toxicity and multiple redox states, Fe is an ideal catalyst for coupling reactions. Recently, green, highly effective and selective reactions have attracted much attention, which accelerated the research of iron catalyzed coupling. Particularly, many new catalyst systems and various reaction types such as iron catalyzed oxidative coupling, reductive coupling and C-H direct functionalization were explored during the past decade. The present review surveys the recent progress in Fe catalyzed C-C coupling concerning their reaction types, including mechanism and application. Furthermore, the prospects of this reaction are also discussed.

Key words: iron catalyzed, C-C coupling reaction, organic synthesis