有机化学 ›› 2018, Vol. 38 ›› Issue (10): 2501-2518.DOI: 10.6023/cjoc201805016 上一篇    下一篇

综述与进展

低价碘催化的氧化偶联反应研究进展

闫溢哲a,b, 崔畅a, 李政a   

  1. a 郑州轻工业学院食品与生物工程学院 郑州 450000;
    b 食品生产与安全河南省协同创新中心 郑州 450000
  • 收稿日期:2018-05-06 修回日期:2018-05-30 出版日期:2018-10-25 发布日期:2018-06-15
  • 通讯作者: 闫溢哲,E-mail:yanyizhe@mail.ustc.edu.cn E-mail:yanyizhe@mail.ustc.edu.cn
  • 基金资助:

    国家自然科学基金(No.21502177)、河南省科技攻关计划(No.182102310903)和郑州轻工业学院博士研究基金(No.2014BSJJ032)资助项目.

Recent Advances in Oxidative Coupling Reaction Catalyzed by Low-Valence Iodine

Yan Yizhea,b, Cui Changa, Li Zhenga   

  1. a School of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou 450000;
    b Henan Collaborative Innovation Center of Food Production and Safety, Zhengzhou 450000
  • Received:2018-05-06 Revised:2018-05-30 Online:2018-10-25 Published:2018-06-15
  • Contact: 10.6023/cjoc201805016 E-mail:yanyizhe@mail.ustc.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21502177), the Scientific and Technological Breakthrough Plan of Henan Province (No. 182102310903) and the Doctoral Research Foundation of Zhengzhou University of Light Industry (No. 2014BSJJ032).

近年来,低价碘催化的氧化偶联反应取得了迅猛的发展,已经成为了一种构建C—C、C—O、C—N、C—S、C—P键及其它化学键的有效方法.与过渡金属催化的氧化偶联反应相比,反应无需过渡金属且条件温和,解决了过渡金属催化剂的高成本和毒性问题,符合绿色化学的要求.因此,碘催化已经引起了化学合成工作者越来越多的重视.综述了2010年至今低价碘催化氧化偶联领域所取得的研究成果,并对该领域进行了展望.

关键词: 低价碘, 氧化偶联, 化学键, 原子经济性

In recent years, low-valence iodine-catalyzed oxidative coupling reaction has made rapid progress, providing an effective method for the construction of C—C, C—O, C—N, C—S, C—P and other chemical bonds. Compared with the transition metal-catalyzed oxidation coupling reaction, this protocol is metal-free under mild conditions. It avoids the high cost and toxicity of transition metal catalyst, which meets the requirements of green chemistry. Therefore, iodine catalysis has attracted much attention of the synthetic chemists. The research progress on low-valence iodine-catalyzed oxidative coupling from 2010 to now is summarized, and outlook of this field is also prospected.

Key words: low-valence iodine, oxidative coupling, chemical bond, atom economy