有机化学 ›› 2019, Vol. 39 ›› Issue (3): 648-660.DOI: 10.6023/cjoc201807056 上一篇    下一篇

综述与进展

聚乙二醇:绿色有机合成的新媒介

肖立伟, 戴富才, 李政, 景学敏, 孔洁, 刘光仙   

  1. 廊坊师范学院化学与材料科学学院 廊坊 065000
  • 收稿日期:2018-07-31 修回日期:2018-10-15 出版日期:2019-03-25 发布日期:2018-11-12
  • 通讯作者: 肖立伟 E-mail:xiaoliwei2000@sina.com
  • 基金资助:

    河北省教育厅重点(No.ZD2016046)资助项目.

Polyethylene Glycol: A New Medium for Green Organic Synthesis

Xiao Liwei, Dai Fucai, Li Zheng, Jing Xuemin, Kong Jie, Liu Guangxian   

  1. Faculty of Chemistry and Material Science, Langfang Normal University, Langfang 065000
  • Received:2018-07-31 Revised:2018-10-15 Online:2019-03-25 Published:2018-11-12
  • Contact: 10.6023/cjoc201807056 E-mail:xiaoliwei2000@sina.com
  • Supported by:

    Project supported by the Educational Commission of Hebei Province (No. ZD2016046).

聚乙二醇(PEG)可以溶解多种有机物和金属配合物,具有良好的热稳定性、难挥发、无毒、能生物降解、廉价易得,易于回收和循环使用.PEG作为绿色介质已经成功地应用到许多有机反应中,如碳-碳偶联反应、碳-杂偶联反应、多组分反应、缩合反应、加成反应、取代反应、氧化反应、还原反应等.总结了近年来PEG作为反应介质在不同有机反应中的应用情况.

关键词: 聚乙二醇, 绿色溶剂, 催化剂载体, 有机合成

Polyethylene glycols (PEG) can dissolve a lot of organic compounds and metallic complexes. Moreover, they are thermally stable, nonvolatile, non-toxic, biodegradable, inexpensive and recyclable. Thus, PEG as green medium has been successfully employed in many organic reactions, such as carbon-carbon coupling reaction, carbon-hetero coupling reaction, multicomponent reaction, condensation reaction, addition reaction, substitution reaction, oxidation reaction, reductive reaction, and so on. The recent advances of PEG applied in orgainc synthesis are reviewed.

Key words: polyethylene glycol (PEG), green solvent, catalyst carrier, organic synthesis