有机化学 ›› 2019, Vol. 39 ›› Issue (2): 550-554.DOI: 10.6023/cjoc201808002 上一篇    下一篇

所属专题: 荧光探针-生物传感合辑 有机超分子化学合辑

研究简报

快速溶剂交换法制备疏水性二氧化硅气凝胶及其负载有机荧光探针的应用研究

王亚飞a, 张涛a,b, 郭旭东a, 胡睿a, 王双青a, 杨国强a   

  1. a 中国科学院化学研究所光化学重点实验室 中国科学院大学 北京 100190;
    b 中国科学院深圳先进技术研究院先进材料中心 深圳 518055
  • 收稿日期:2018-08-05 修回日期:2018-09-06 出版日期:2019-02-25 发布日期:2018-09-26
  • 通讯作者: 王双青, 杨国强 E-mail:g1704@iccas.ac.cn;gqyang@iccas.ac.cn
  • 基金资助:

    国家自然科学基金(Nos.21873106,21627802)资助项目.

Preparation of Hydrophobic SiO2 Aerogel by Rapid Solvents Exchange Method and Its Application Loaded with Organic Fluorescence Probe

Wang Yafeia, Zhang Taoa,b, Guo Xudonga, Hu Ruia, Wang Shuangqinga, Yang Guoqianga   

  1. a Key Laboratory of Photochemistry, Institute of Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100190;
    b Center of Advanced Material Research, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055
  • Received:2018-08-05 Revised:2018-09-06 Online:2019-02-25 Published:2018-09-26
  • Contact: 10.6023/cjoc201808002 E-mail:g1704@iccas.ac.cn;gqyang@iccas.ac.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21873106, 21627802).

气凝胶是流动相为气体的凝胶材料,具有低密度、高孔隙率的特性,有着广泛的应用前景.本工作开发了一种快速溶剂交换法,利用原位二级萃取的原理,通过乙醇-二氯甲烷-水三种溶剂间互溶-不互溶的特性实现了气凝胶制备中的快速溶剂交换,结合疏水性处理和减压干燥得到了疏水性二氧化硅气凝胶.所得到的气凝胶密度低,与水的接触角达到155.8°.该气凝胶可以负载多种有机荧光探针染料,可以有效避免由于探针分子聚集而引起的荧光猝灭,将有可能使有机荧光探针在更广泛的领域得到实际应用.

关键词: 气凝胶, 有机荧光探针, 制备, 快速溶剂交换法, 应用

Aerogel is a kind of gel materials, of which the fluid phase is gas. Aerogel has the characteristics of low density and high porosity, and has a wide application prospects. In this work, a rapid solvents exchange method was developed, and using in-situ secondary extraction, rapid solvents exchange in aerogel preparation was achieved through the miscibility and immiscibility of ethanol-dichloromethane-water. Combined with hydrophobic treatment and vacuum drying, hydrophobic silica aerogel was obtained. The aerogel had a low density and a contact angle with water of 155.8°. The aerogel can load various organic fluorescent probe dyes, which can effectively avoid the fluorescence quenching caused by the aggregation of the probe molecules, which it will expand the practical application range of the organic fluorescent probes in wider fields.

Key words: aerogel, organic fluorescence probe, preparation, rapid solvents exchange method, application