关键词: 桥环化合物, 环加成, 串联反应

Bridged rings are frequently encountered in natural products and biologically active molecules, which have significant application in the field of medicinal chemistry, natural product chemistry, synthetic chemistry, material chemistry and life science. In recent years, with the unremitting efforts of a large number of chemists, a series of new methods have been developed for the efficient synthesis of bridged compounds. In this review, we wish to summarize the detailed synthetic methods to access bridged compounds in the past five years involving cycloadditions and cascade reactions, and to briefly analyze the advantages and problems of the current methods, which would provide useful reference for the researchers engaged in organic synthesis and related fields.

Key words: Bridged rings, Cycloadditions, Cascade reactions