有机化学 ›› 2013, Vol. 33 ›› Issue (09): 1884-1890.DOI: 10.6023/cjoc201302025 上一篇    下一篇

综述与进展

1-单取代-1,2,3-三唑环的构建进展

江玉波a, 韩春美b, 梁雪秋a, 杨朋a, 王红a   

  1. a 昆明理工大学理学院 昆明 650093;
    b 昆明理工大学机电工程学院 昆明 650093
  • 收稿日期:2013-02-28 修回日期:2013-03-19 出版日期:2013-09-28 发布日期:2013-04-12
  • 通讯作者: 江玉波 E-mail:ybjiang@kmust.edu.cn
  • 基金资助:

    国家自然科学基金(No. 21262020);云南省科技厅(No. KKSY201207047)资助项目

Advances in the Construction of 1-Monosubstituted 1,2,3-Triazole Ring

Jiang Yuboa, Han Chunmeib, Liang Xueqiua, Yang Penga, Wang Honga   

  1. a Faculty of Science, Kunming University of Science and Technology, Kunming 650500;
    b School of Mechanical and Electronic Engineering, Kunming University of Science and Technology, Kunming 650500
  • Received:2013-02-28 Revised:2013-03-19 Online:2013-09-28 Published:2013-04-12
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21262020) and the Science and Technology Planning Project of Yunnan Province (No. KKSY201207047)

随着1,2,3-三唑衍生物应用范围的扩大, 该类化合物的合成在近几年引起了广泛关注并获得了快速发展. 1-单取代-1,2,3-三唑衍生物比其他类型三唑的杂环构建难度大, 主要原因是合成该类产物“炔源”的结构要求独特, 并需要相应特殊的反应条件. 综述了该类杂环的构建研究进展, 按照“炔源”的种类不同分别阐述了各种构建方法, 主要包括乙炔、取代乙炔、乙烯化物等, 并对部分重要的反应机理进行了分析.

关键词: 1-单取代, 1,2,3-三唑, 乙炔, 取代乙炔, 乙烯化物

As the 1,2,3-triazole derivatives were used in many expanding areas, its preparation has attracted much attention and obtained encouraging progress in recent years. The construction of the ring of monosubstituted 1,2,3-triazoles is more difficult than that of the other kinds of these heterocycles, owing to the special request for the structure of "alkyne source" and the relatively rigorous reaction conditions required in the system. This review covers the recent construction advances of the heterocycles based on the different moieties, such as acetylene, substituted acetylene, vinyl compounds, and others. Some important mechanisms were also discussed in details.

Key words: 1-monosubstituted, 1,2,3-triazoles, acetylene, substituted acetylene, vinyl compounds