有机化学 ›› 2014, Vol. 34 ›› Issue (10): 1941-1957.DOI: 10.6023/cjoc201405003 上一篇    下一篇

综述与进展

单质碘促进的有机反应研究进展

赵巾巾, 高文超, 常宏宏, 李兴, 刘强, 魏文珑   

  1. 太原理工大学化学化工学院生物与制药工程系 太原 030024
  • 收稿日期:2014-05-04 修回日期:2014-06-02 出版日期:2014-10-25 发布日期:2014-06-23
  • 通讯作者: 高文超, 常宏宏 E-mail:gaowenchao@tyut.edu.cn;changhonghong@tyut.edu.cn
  • 基金资助:

    山西省自然科学基金(Nos. 2012021007-2,2011011010-2)、山西省高等学校科技创新基金(No. 20120006)、太原理工大学引进人才启动经费(No. tyut-rc201307a)资助项目.

Recent Advances in Iodine-Mediated Organic Reactions

Zhao Jinjin, Gao Wenchao, Chang Honghong, Li Xing, Liu Qiang, Wei Wenlong   

  1. College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan 030024
  • Received:2014-05-04 Revised:2014-06-02 Online:2014-10-25 Published:2014-06-23
  • Supported by:

    Project supported by the Natural Science Foundation of Shanxi Province (Nos. 2012021007-2, 2011011010-2), the Scientific and Technologial Innovation Programs of Higher Education Institutions in Shanxi Province (No. 20120006), and the Qualified Personnel Foundation of Taiyuan University of Technology (No. tyut-rc201307a).

单质碘作为有机化学中结构最为简单的反应试剂之一,其促进的有机转化在最近几年越来越受到人们的关注.总结了单质碘的氧化性,酸性和亲电性3类基本化学性质,并针对3类性质所涉及的相关反应性报道进行了介绍. 除此之外,还总结了近5年来单质碘作为催化剂在杂环合成,偶联反应,及C—H官能团转化等方面的应用.

关键词: 单质碘, 氧化, 酸性, 亲电环化, 杂环合成, 有机催化

As one of simplest chemical reagents, iodine has promoted diverse organic transformations, which have attracted much attention in recent years. The present review summarizes three basic chemical features of iodine in organic synthesis: the oxidative reactivity, the acidic reactivity and the electrophilic reactivity, along with the introduction of corresponding representative examples. Furthermore, the iodine-catalyzed reactions involed in the synthesis of heterocycles, organic coupling reactions, the C-H functionalization, and other applications are also presented in this review.

Key words: iodine, oxidation, acidity, electrophilic cyclisation, heterocycle syntheses, organocatalysis