有机化学 ›› 2015, Vol. 35 ›› Issue (2): 362-372.DOI: 10.6023/cjoc201409007 上一篇    下一篇

综述与进展

三联苯类化合物合成方法的研究进展

石巍, 俞婷婷, 崔冬梅   

  1. 浙江工业大学药学院 杭州 310014
  • 收稿日期:2014-09-05 修回日期:2014-10-16 出版日期:2015-02-25 发布日期:2014-10-30
  • 通讯作者: 崔冬梅 E-mail:cuidongmei@zjut.edu.cn;shiwei_217@163.com
  • 基金资助:

    浙江省自然科学基金(No. Y4100558)资助项目.

Advances in the Synthetic Methods of Terphenyls

Shi Wei, Yu Tingting, Cui Dongmei   

  1. College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014
  • Received:2014-09-05 Revised:2014-10-16 Online:2015-02-25 Published:2014-10-30
  • Supported by:

    Project supported by the Natural Science Foundation of Zhejiang Province (No. Y4100558).

三联苯类化合物具有免疫抑制、抗氧化、神经保护、细胞毒以及抗血栓等多种生物活性, 同时在液晶材料方面也有着广泛的应用. 因此该类化合物的合成备受人们的关注. 以偶联、环合、脱氢等反应进行分类, 综述了近年合成该类化合物的方法. 通过该角度的综述, 我们希望能为设计出更好的合成方法带来启示.

关键词: 三联苯, 偶联反应, 环合反应, 合成

Terphenyl derivatives possess various biological activities, such as immunosuppressants, antioxidants, neuroprotective activity, cytotoxic activity, and antithrombotic activity, and they are also widely used in liquid crystal materials. Significant effort has been devoted to the synthesis of such compounds. Classified into coupling reaction, cycloaddition, dehydrogenation and other methods, this review provides a summary of recently developed methods for the preparation of terphenyls.

Key words: terphenyls, coupling reaction, cycloaddition reaction, synthesis