有机化学 ›› 2016, Vol. 36 ›› Issue (2): 258-273.DOI: 10.6023/cjoc201509030 上一篇    下一篇

综述与进展

过渡金属催化烯丙醇异构化反应的研究进展

钟业辛a, 任凯b, 谢小敏b, 张兆国a,b   

  1. a 上海应用技术学院化学与环境工程学院 上海 201418;
    b 上海交通大学化学化工学院 上海 200240
  • 收稿日期:2015-09-24 修回日期:2015-10-23 出版日期:2016-02-25 发布日期:2015-11-03
  • 通讯作者: 任凯, 张兆国 E-mail:kairenhb@sjtu.edu.cn;zhaoguo@sjtu.edu.cn
  • 基金资助:

    国家自然科学基金(No. 21472124)资助项目

Transition Metal Catalyzed Isomerization Reaction of Allylic Alcohols

Zhong Yexina, Ren Kaib, Xie Xiaominb, Zhang Zhaoguoa,b   

  1. a School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418;
    b School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240
  • Received:2015-09-24 Revised:2015-10-23 Online:2016-02-25 Published:2015-11-03
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21472124).

羰基化合物是一类重要的有机合成中间体, 其在医药、农药、香料和化妆品领域具有重要应用. 近年来, 利用烯丙醇异构化反应快速合成一系列羰基化合物和构建新化合物的方法受到化学家的广泛关注. 由于过渡金属催化的烯丙醇异构化反应具有良好的原子经济性, 在合成方面具有独特的优势, 烯丙醇异构化反应成为金属有机化学研究的热点之一. 综述了近年来过渡金属催化的烯丙醇异构化反应的研究进展和应用.

关键词: 烯丙醇, 过渡金属, 异构化反应, 羰基化合物, 不对称异构化反应, 串联反应

Carbonyl compounds are key synthetic intermediates in the fields of medicine, pesticide, perfumes and cosmetics. In recent years, transition metal catalyzed isomerization of allylic alcohols to synthesize various carbonyl compounds has drawn much attention and been explored extensively, due to their high atomic economy and unique superiority. The recent development of the isomerization reactions of allylic alcohols catalyzed by various transition metals is summarized.

Key words: allylic alcohols, transition metal, isomerization reaction, carbonyl compounds, asymmetric isomerization reaction , tandem reaction