有机化学 ›› 2016, Vol. 36 ›› Issue (1): 43-59.DOI: 10.6023/cjoc201508012 上一篇    下一篇

综述与进展

钯催化的串联反应构建苯并五元杂环的研究进展

丁刚a,b, 王泽宇a, 殷中琼c, 乐贵洲a,b   

  1. a 四川农业大学理学院 雅安 625014;
    b 四川农业大学农学院 成都 611130;
    c 四川农业大学动物医学院 成都 611130
  • 收稿日期:2015-08-10 修回日期:2015-11-02 出版日期:2016-01-25 发布日期:2015-11-06
  • 通讯作者: 乐贵洲 E-mail:yueguizhou@sicau.edu.cn
  • 基金资助:

    四川省科技厅应用基础项目基金(No. 2012JY0118)和四川农业大学资助项目.

Progress in Palladium-Catalyzed Tandem Reaction of Constructing Benzo-Five-Membered Heterocycles

Ding Ganga,b, Wang Zeyua, Yin Zhongqiongc, Yue Guizhoua,b   

  1. a College of Science, Sichuan Agricultural University, Ya'an, 625014;
    b College of Agricultural Sciences, Sichuan Agricultural University, Chengdu 611130;
    c College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130
  • Received:2015-08-10 Revised:2015-11-02 Online:2016-01-25 Published:2015-11-06
  • Supported by:

    Project supported by the Science & Technology Department of Sichuan Province (No. 2012JY0118) and the Sichuan Agricultural University.

苯并五元杂环是许多重要天然产物的骨架之一. 近年来, 过渡金属催化的串联反应能够在“一锅煮”的条件下构建多根化学键, 其中钯催化的串联反应受到广泛关注. 总结了自2000年以来钯催化的串联反应合成苯并五元杂环及其衍生物的文献.

关键词: 杂环, 串联反应, 钯催化剂, 合成

The benzo-five-membered heterocycles existed extensively in many important natural products and also showed excellent bioactivites. Therefore, organic chemists around the world made efforts to develop the highly efficient methods of constructing these heterocycles. Recently, the syntheses of them via transition metal-catalyzed tandem reaction, especially palladium-catalyzed reaction, have been reported widely. This review emphasizes on the palladium-catalyzed tandem reaction of the formation of benzo-five-membered heterocycles and their derivatives reported since 2000.

Key words: heterocycle, tandem reaction, palladium catalyst, synthesis