有机化学 ›› 2019, Vol. 39 ›› Issue (5): 1277-1283.DOI: 10.6023/cjoc201811023 上一篇    下一篇

综述与进展

多取代呋喃合成最新研究进展

张文生a, 许文静a, 张斐b, 李焱a   

  1. a 焦作师范高等专科学校 焦作 454100;
    b 焦作职业技术学校 焦作 454100
  • 收稿日期:2018-11-18 修回日期:2018-12-25 出版日期:2019-05-25 发布日期:2019-01-18
  • 通讯作者: 张文生 E-mail:tongjizws@163.com
  • 基金资助:

    河南省基础与前沿技术研究计划(自然科学基金)(No.162300410270)资助项目.

Recent Progress in Synthesis of Polysubstituted Furans

Zhang Wenshenga, Xu Wenjinga, Zhang Feib, Li Yana   

  1. a Jiaozuo Teachers College, Jiaozuo 454100;
    b Jiaozuo Vocational and Technological School, Jiaozuo 454100
  • Received:2018-11-18 Revised:2018-12-25 Online:2019-05-25 Published:2019-01-18
  • Contact: 10.6023/cjoc201811023 E-mail:tongjizws@163.com
  • Supported by:

    Project supported by the Foundation and Frontier Research Program (the Natural Science Foundation) of Henan Province (No. 162300410270).

呋喃是一类重要的五元含氧杂环化合物,其不仅是许多天然产物、药物和生物活性分子的核心结构,而且还是重要的有机合成中间体,具有广泛的应用价值.因此,呋喃及其衍生物的合成一直是有机化学家关注的研究热点之一.对2013年以来多取代呋喃的合成新方法进行了综述,包括二取代、三取代、四取代呋喃和苯并呋喃等.

关键词: 呋喃, 合成, 环化反应

Furan, an important class of oxygen-containing five-membered heterocyclic compounds, is not only the fundamental structure of many natural products, drugs and biologically active molecules, but also an valuable intermediate in organic synthesis. Synthesis of polysubstituted furans has been one of the focus of organic chemists. In this paper, recent progress in the synthesis of polysubstituted furans since 2013, including disubstituted, trisubstituted, tetrasubstituted furans and benzofurans is reviewed.

Key words: furan, synthesis, cyclization