有机化学 ›› 2019, Vol. 39 ›› Issue (5): 1396-1403.DOI: 10.6023/cjoc201811039 上一篇    下一篇

研究论文

三氯异氰尿酸促进下腙的氯化反应研究

宗吴中, 胡雨来, 王小平, 刘佳欣, 黄丹凤, 王克虎   

  1. 西北师范大学化学化工学院 兰州 730070
  • 收稿日期:2018-11-30 修回日期:2019-01-17 出版日期:2019-05-25 发布日期:2019-01-31
  • 通讯作者: 胡雨来 E-mail:huyl@nwnu.edu.cn
  • 基金资助:

    国家自然科学基金(No.21662030)资助项目.

Study on the Chlorination Reaction of Hydrazones by Using of Trichloroisocyanuric Acid as Chloride Source

Zong Wuzhong, Hu Yulai, Wang Xiaoping, Liu Jiaxin, Huang Danfeng, Wang Kehu   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
  • Received:2018-11-30 Revised:2019-01-17 Online:2019-05-25 Published:2019-01-31
  • Contact: 10.6023/cjoc201811039 E-mail:huyl@nwnu.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21662030).

以三氯异氰尿酸为氯源,探索了腙和三氟乙醛芳腙的氯化反应,高产率地得到了一系列氯代芳腙和三氟乙酰氯芳腙化合物.该方法具有反应条件温和,反应时间短,易于操作,氯源稳定、价格低廉等特点,提供了一种高效合成氯代芳腙及三氟乙酰氯芳腙的新方法.

关键词: 三氯异氰尿酸, 氯化反应, 氯代芳腙, 三氟乙酰氯芳腙, 合成

The chlorination reaction of hydrazones with N-aryltrifluoroacetohydrazones by using trichloroisocyanuric acid as chlorine source was investigated, and a series of N-arylhydrazonyl chlorides and N-aryltrifluoroacetohydrazonyl chlorides were obtained in high yields. This method had advatages of easy operation, short reaction time, mild conditions and the use of stable and cheap chlorine source, which provides an efficiant method for the synthesis of N-arylhydrazonyl chlorides and N-aryltrifluoroacetohydrazonyl chlorides.

Key words: trichloroisocyanuric acid, chlorination reaction, hydrazonyl chlorides, trifluoroacetohydrazonyl chlorides, synthesis