有机化学 ›› 2019, Vol. 39 ›› Issue (7): 1846-1857.DOI: 10.6023/cjoc201901033 上一篇    下一篇

综述与进展

多功能荧光探针的设计、合成与应用研究进展

陈思鸿a, 庞楚明a, 陈孝云b, 严智浩a, 黄诗敏a, 李香弟a, 钟雅婷a, 汪朝阳a   

  1. a 华南师范大学化学与环境学院 教育部环境理论化学重点实验室 广州 510006;
    b 江苏科技大学环境与化学工程学院 镇江 212003
  • 收稿日期:2019-01-22 修回日期:2019-03-08 出版日期:2019-07-25 发布日期:2019-04-09
  • 通讯作者: 陈孝云, 汪朝阳 E-mail:wangzy@scnu.edu.cn;xiaoyun_chen12@163.com
  • 基金资助:

    广东省自然科学基金(No.2014A030313429)、广州市科技计划科学研究专项(No.201607010251)、江苏省自然科学基金(No.BK20160551)、国家自然科学基金(No.21602085)、广东省科技计划(No.2017A010103016)、华南师范大学大创计划(No.20191434)资助项目.

Research Progress in Design, Synthesis and Application of Multifunctional Fluorescent Probes

Chen Sihonga, Pang Chuminga, Chen Xiaoyunb, Yan Zhihaoa, Huang Shimina, Li Xiangdia, Zhong Yatinga, Wang Zhaoyanga   

  1. a School of Chemistry and Environment, South China Normal University, Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, Guangzhou 510006;
    b School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003
  • Received:2019-01-22 Revised:2019-03-08 Online:2019-07-25 Published:2019-04-09
  • Contact: 10.6023/cjoc201901033 E-mail:wangzy@scnu.edu.cn;xiaoyun_chen12@163.com
  • Supported by:

    Project supported by the Natural Science Foundation of Guangdong Province (No. 2014A030313429), the Guangzhou Science and Technology Project Scientific Special (No. 201607010251), the Natural Science Foundation of Jiangsu Province (No. BK20160551), the National Natural Science Foundation of China (No. 21602085), the Guangdong Provincial Science and Technology Project (No. 2017A010103016), and the Undergraduates Innovation Project of South China Normal University (No. 20191434).

多功能荧光探针可检测多个阴阳离子、小分子等,相对于单分析的荧光探针能提高检测效率、降低分析成本,故广受关注.根据分子结构特点,将多功能荧光探针分为有机小分子型、聚合物型和金属有机配合物型等三大类,从检测对象和性能出发,重点综述了近几年国内外多功能荧光探针在分子设计、合成与检测应用等方面的新进展,并展望了多功能荧光探针的发展潜力,指出开发能够在同体系中同时识别多个分析物的探针是未来研究中的重点方向.

关键词: 多功能, 荧光探针, 设计与合成, 检测机理, 传感应用

The multifunctional fluorescent probes can detect a plurality of anions and cations or other small molecules. These probes can greatly improve the detection efficiency and reduce the analysis cost with respect to the mono-analyte fluorescent probes. Thus, they have attracted much attention in recent years. According to their molecular structural characteristics, the reported multifunctional fluorescent probes are divided into three types as organic small molecules, polymers and metal-organic complexes. The new progress on their molecular design, synthesis and detecting application is reviewed on the viewpoint of sensing objects and performances. The developing potential of multifunctional fluorescent probes is envisioned also, and the probes capable of simultaneously identifying multiple analytes in the same system should be highlighted in the future

Key words: multifunctional, fluorescent probe, design and synthesis, detection mechanism, sensing application