有机化学 ›› 2019, Vol. 39 ›› Issue (5): 1316-1322.DOI: 10.6023/cjoc201903009 上一篇    下一篇

研究论文

芳香磺酰肼与胺通过铜催化氧化偶联合成芳香磺酰胺

张振雷, 钱朋, 查正根   

  1. 中国科学技术大学化学与材料学院 合肥 230026
  • 收稿日期:2019-03-05 修回日期:2019-03-26 出版日期:2019-05-25 发布日期:2019-04-19
  • 通讯作者: 张振雷, 查正根 E-mail:helenken@mail.ustc.edu.cn;zgzha@ustc.edu.cn
  • 基金资助:

    国家自然科学基金(Nos.21672200,21472177)资助项目.

Copper-Catalyzed Aerobic Oxidative Coupling of Aromatic Sulfonyl Hydrazides with Amines:A New Access to Aromatic Sulfonamides

Zhang Zhenlei, Qian Peng, Zha Zhenggen   

  1. School of Chemistry and Materials Science, University of Science and Technology of China, Hefei 230026
  • Received:2019-03-05 Revised:2019-03-26 Online:2019-05-25 Published:2019-04-19
  • Contact: 10.6023/cjoc201903009 E-mail:helenken@mail.ustc.edu.cn;zgzha@ustc.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21672200, 21472177).

报道了在铜催化的条件下,芳香磺酰肼与各种胺氧化偶联合成芳香磺酰胺化合物.相比于传统的合成磺酰胺方法,该合成方法利用铜和氧气作为氧化体系,无需额外添加其他氧化剂,副产物只有氮气,是一个比较绿色的合成磺酰胺类化合物的方法.

关键词: 铜催化, 磺酰肼, 磺酰胺

A copper(Ⅱ)-catalyzed aerobic oxidative coupling of aromatic sulfonyl hydrazides with amines for the synthesis of aromatic sulfonamides was described. In contrast to previously described methods, this reaction employs copper/O2 as the catalytic system, and generates N2 as the only byproduct, which provides an environmentally benign synthetic route for aromatic sulfonamides.

Key words: copper catalysis, sulfonyl hydrazide, sulfonamide