Chin. J. Org. Chem. ›› 2012, Vol. ›› Issue (03): 608-611.DOI: 10.6023/cjoc1108011 Previous Articles     Next Articles



吴利欢, 郭海福, 黄新仪, 吴瑞芬   

  1. 肇庆学院化学化工学院 肇庆 526060
  • 收稿日期:2011-08-01 修回日期:2011-09-18 发布日期:2012-03-24
  • 通讯作者: 吴利欢
  • 基金资助:

    肇庆市科技创新计划(No. 2009G12)和广东省自然科学基金(No. 07010338)资助项目.

Synthesis and Structure Characterization of Novel 3-Substituted-(thio)chroman-4-one Derivatives

Wu Lihuan, Guo Haifu, Wang Xinyi, Wu Ruifen   

  1. School of Chemistry and Chemical Engineering, Zhaoqing University, Zhaoqing 526060
  • Received:2011-08-01 Revised:2011-09-18 Published:2012-03-24
  • Supported by:

    Project supported by the Scientific and Technological Innovation of Zhaoqing City (No. 2009G12) and the Natural Science Foundation of Guangdong Province (No. 07010338).

A series of novel 3-substituted-(thio)chroman-4-one derivatives 3a~3l were synthesized by the condensation of substituted (unsubstituted)-(thio)chromanone with aromatic aldehydes in the presence of sodium hydroxide, via two different methods of conventional solvent method and solvent-free grinding method which has advantages of simple work-up procedure, shorter reaction time, milder conditions and environ-mental friendliness. The structures of the title compounds 3a~3l were characterized by IR, 1H NMR, 13C NMR and MS techniques.

Key words: chromanone, solvent-free, grinding