Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (01): 101-105.DOI: 10.6023/cjoc201208019 Previous Articles     Next Articles



孙娜波a, 童建颖a, 武宏科b   

  1. a 浙江树人大学生物与环境学院 杭州 310015;
    b 浙江工业大学化学工程与材料学院 杭州 310014
  • 收稿日期:2012-08-20 修回日期:2012-10-07 发布日期:2012-10-12
  • 通讯作者: 孙娜波, 武宏科;
  • 基金资助:

    浙江省教育厅基金(No. Y200803060)资助项目.

Synthesis and Fungicidal Activity of 1,3,4-Oxadiazole Derivatives Containing Pyrazole Moiety

Sun Naboa, Tong Jianyinga, Wu Hongkeb   

  1. a College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015;
    b College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014
  • Received:2012-08-20 Revised:2012-10-07 Published:2012-10-12
  • Supported by:

    Project supported by the Program of Education Department of Zhejiang Province (No. Y200803060).

A series of novel 1,3,4-oxadiazole derivatives were synthesized from acetylacetone, hydrazine hydrate by multi-step reactions. Their structures were characterized by 1H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities against Corynespora cassiicola, Pseudomonas syringae pv. Lachrymans, Pseudoperonospora cubensis and Sclerotinia sclerotiorum in vivo, and the results indicated that some of the title compounds displayed excellent fungicidal activities.

Key words: 1,3,4-oxadiazole, pyrazole, synthesis, fungicidal activity