Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (02): 375-377.DOI: 10.6023/cjoc201209027 Previous Articles     Next Articles



周德军a,b, Matsuya Yujib   

  1. a 河南理工大学物理化学学院 焦作 454000;
    b 富山大学药学部 日本富山 930-0194
  • 收稿日期:2012-09-19 修回日期:2012-10-24 发布日期:2012-11-15
  • 通讯作者: 周德军,
  • 基金资助:

    河南理工大学博士启动基金(No. 648536)资助项目.

Synthesis of 6-Trimethylsilyl-α-pyrone from 2,6-Bis(trimethylsilyl)- pyran via Mild Aerobic Oxidation

Zhou Dejuna,b, Yuji Matsuyab   

  1. a School of Physics and Chemistry, Henan Polytechnic University, Jiaozuo 454000, China;
    b Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan
  • Received:2012-09-19 Revised:2012-10-24 Published:2012-11-15
  • Supported by:

    Project supported by the Doctoral Fund of Henan Polytechnic University (No. 648536).

In this study, an effective and mild method for the synthesis of 6-trimethylsilyl-α-pyrone was successfully developed. 6-Trimethylsilyl-α-pyrone, a very important intermediate in organic synthesis, was mildly synthesized from pyrane derivative via an aerobic oxidation at room temperature, without any solvents and catalysts. Furthermore, the possible mechanism of the reaction was proposed.

Key words: 6-trimethylsilyl-α-pyrone, oxidation, mechanism