Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (2): 309-324.DOI: 10.6023/cjoc201409021 Previous Articles     Next Articles



翁官欢a,b, 朱彬b, 叶杨b, 李世军b   

  1. a 台州学院医药化工学院 台州 318000;
    b 杭州师范大学材料与化学化工学院 杭州 310036
  • 收稿日期:2014-09-09 修回日期:2014-10-24 发布日期:2014-11-13
  • 通讯作者: 翁官欢, 李世军;
  • 基金资助:

    国家自然科学基金(Nos. 21072039, 91127010)、教育部创新团队(No. IRT1231)、浙江省自然科学基金(No. LZ13B030001)资助项目.

Acid/Base-Controllable Molecular Machines and Molecular Switches

Weng Guan-Huana,b, Zhu Binb, Ye Yangb, Li Shijunb   

  1. a College of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318000;
    b College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036
  • Received:2014-09-09 Revised:2014-10-24 Published:2014-11-13
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21072039, 91127010), the Program for Changjiang Scholars and Innovative Research Team in Chinese University (No. IRT1231), and the Zhejiang Provincial Natural Science Foundation of China (No. LZ13B030001).

There are three kinds of energy-supplied modes to drive artificial molecular machines: chemical stimulation, electrochemical input and light stimulation. The basic principle of acid/base-controlled (or pH-operated) method is to change the chemical properties of components in the system by adjusting pH of the solution via adding acid/base compounds, to realize the movements of components, which belongs to chemical stimulation mode. The acid/base controlled method has been one of the most useful energy-driven modes for artificial molecular machines. This article summarizes the recent studies on acid/base- controllable molecular machines or molecular switches. The synthesis and operation of acid/base-controllable artificial molecular switches and molecular machines based on crown ethers and other macrocyclic hosts are reviewed. They exhibited great potential in the applications for information storage materials, electronic devices, and drug delivery.

Key words: molecular machines, molecular recognition, crown ethers, cryptands, host-guest compounds, rotaxanes, supramolecular chemistry, molecular devices