Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (9): 2091-2104.DOI: 10.6023/cjoc201604034 Previous Articles     Next Articles



刘楝a,b, 周淑晶a, 孙炳峰b   

  1. a 佳木斯大学药学院 佳木斯 154007;
    b 中国科学院上海有机化学研究所 中国科学院天然产物有机合成化学重点实验室 上海 200032
  • 收稿日期:2016-04-17 修回日期:2016-05-10 发布日期:2016-05-17
  • 通讯作者: 周淑晶, 孙炳峰;
  • 基金资助:


Progresses in Total Synthesis of Platencin

Liu Liana,b, Zhou Shujinga, Sun Bingfengb   

  1. a School of Pharmacy, Jiamusi University, Jiamusi 154007;
    b Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2016-04-17 Revised:2016-05-10 Published:2016-05-17
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos.21172246, 21290180, 21472210), and the Youth Innovation Promotion Association CAS (No.2012202).

Platencin was isolated from a new strain of Streptomyces platensis MA7339 found in a soil sample collected in Spain. It has a novel molecular structure and exhibits a broad spectrum of antibacterial activity. In this review, the progresses since 2010 in the total synthesis of platencin are summarized with an emphasis on the synthetic strategies of the routes.

Key words: platencin, total synthesis, synthetic strategy