Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (1): 47-78.DOI: 10.6023/cjoc201606024 Previous Articles     Next Articles



高安丽, 叶青松, 余娟, 刘伟平   

  1. 昆明贵金属研究所 稀贵金属综合利用新技术国家重点实验室 昆明 650106
  • 收稿日期:2016-06-14 修回日期:2016-08-12 发布日期:2016-09-01
  • 通讯作者: 刘伟平
  • 基金资助:

    国家“十二五”科技支撑计划课题(No. 2012BAE06B08)和云南省科技创新强者计划(Nos. 2015AA006,2013B019)资助项目.

Research Advances of the Chiral Binap-Ru(II) Catalysts in Asymmetric Hydrogenation Reactions

Gao Anli, Ye Qingsong, Yu Juan, Liu Weiping   

  1. State Key Laboratory of Advanced Technologies for Comprehensive Utilization of Platinum Metals, Kunming Institute of Precious Metals, Kunming 650106
  • Received:2016-06-14 Revised:2016-08-12 Published:2016-09-01
  • Supported by:

    Project supported by the 12th National Scientific Support Plan(No. 2012BAE06B08) and the Yunnan Province Scientific Creative Plan(Nos. 2015AA006, 2013B019).

Chiral 2,2'-bis(diphenylphosphino)-1,1'-binapthyl(Binap) ligand consists of a pair of 2-diphenylphosphinonaphthyl groups connected at the 1 and 1'positions,being of the nature of the C2-axial chirality with optical activity of ±234°.The Binap can coordinate with many transitional metals to form stable chelation complexes,effecting the chirality transfer to the metal center for function in asymmetrically catalytic reactions.This contribution is focused on the Binap-Ru(Ⅱ) catalytic system that covers the various substrates,reaction conditions,enantioselectivity of the products,reaction mechanism,and others on the basis of the prepared stable Binap-Ru(Ⅱ) complexes as the clue in the text.This study will give a deep understanding of this system especially concerning the applied catalytic synthesis of the useful organic molecules.

Key words: Binap ligand, chiral ruthenium complexes, asymmetric catalysis, reaction mechanism, application