Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (6): 1407-1411.DOI: 10.6023/cjoc201701040 Previous Articles     Next Articles



王金涛, 熊就凯, 李娟娟, 王佳利, 王克让, 李小六   

  1. 河北大学化学与环境科学学院 药物化学与分子诊断教育部重点实验室 河北省化学生物学重点实验室 保定 071002
  • 收稿日期:2017-01-20 修回日期:2017-02-19 发布日期:2017-02-27
  • 通讯作者: 王克让,李小六;
  • 基金资助:


Hydrogenation of Alkynes to cis-Alkenes with Hydrazine in Air

Wang Jintao, Xiong Jiukai, Li Juanjuan, Wang Jiali, Wang Kerang, Li Xiaoliu   

  1. Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Key Laboratory of ChemicalBiology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002
  • Received:2017-01-20 Revised:2017-02-19 Published:2017-02-27
  • Contact: 10.6023/cjoc201701040;
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21372059, 21572044), and the Natural Science Foundation of Hebei Province (Nos. B2016201254, 2016201031).

Transfer hydrogenation is a mild and effective way in reduction reaction. In this paper, a simple approach of selectively hydrogenation of alkynes to cis-alkenes with NH2NH2·H2O as a transfer hydrogenation agent in the presence of air without any catalysts or metals was developed. Furthermore, the configuration of cis-alkene was confirmed by the 2D NOESY spectrum.

Key words: transfer hydrogenation, hydrazine, alkynes, alkenes, diazene