Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (10): 2491-2500.DOI: 10.6023/cjoc201805001 Previous Articles     Next Articles



颜廷斌, 刘跃辉, 沈悦海   

  1. 昆明理工大学生命科学与技术学院 昆明 650500
  • 收稿日期:2018-05-02 修回日期:2018-06-12 发布日期:2018-06-29
  • 通讯作者: 沈悦海,
  • 基金资助:


Hydrogen-Bonding Effects in Ruthenium-Catalyzed Olefin Metathesis

Yan Tingbin, Liu Yuehui, Shen Yuehai   

  1. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500
  • Received:2018-05-02 Revised:2018-06-12 Published:2018-06-29
  • Contact: 10.6023/cjoc201805001
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21662022).

Olefin metathesis is among the most popular synthetic methods over the past two decades. Owing to the good functional group tolerance of ruthenium catalysts, hydrogen bonding has emerged as a powerful controlling element for olefin metathesis recently. Recent studies demonstrated that the hydrogen bonding between ruthenium catalyst and certain types of substrates or additives could significantly improve the rate, chemoselectivity and stereoselectivity of olefin metathesis, while the self-assembly of substrates could be driven by intramolecular or intermolecular hydrogen bonding and result in highly selective reactions. In this review, the development and application of hydrogen bonding-promoted ruthenium-catalyzed olefin metathesis reactions are summarized, and the mechanism insights into these systems are highlighted.

Key words: olefin metathesis, ruthenium-carbene complex, catalysis, hydrogen bonding