Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (3): 625-647.DOI: 10.6023/cjoc201808031 Previous Articles     Next Articles

Reviews

烯烃的双官能团化反应研究进展

付晓飞a, 赵文献a,b   

  1. a 郑州大学化学与分子工程学院 郑州 450000;
    b 商丘师范学院化学化工学院 商丘 476000
  • 收稿日期:2018-08-27 修回日期:2018-11-01 出版日期:2019-03-25 发布日期:2018-11-26
  • 通讯作者: 赵文献 E-mail:zhwx2595126@163.com
  • 基金资助:

    国家自然科学基金(Nos.20972091,21172139)、河南省高等学校重点科研(No.16A150020)资助项目.

Progress in Difunctionalization of Alkenes

Fu Xiaofeia, Zhao Wenxiana,b   

  1. a College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450000;
    b College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000
  • Received:2018-08-27 Revised:2018-11-01 Online:2019-03-25 Published:2018-11-26
  • Contact: 10.6023/cjoc201808031 E-mail:zhwx2595126@163.com
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 20972091, 21172139) and the Key Science Research of Education Committee in Henan Province (No. 16A150020).

As an important kind of organic chemical reaction, difunctionalization of alkenes can not only synthesize multi-site reaction products effectively in one step, but also transform the starting material into other compounds that containing biological activity or drug activity. At the same time, it provides more methods for the construction of chemical structure diversity, so it is very important to develop the bifunctionalization of alkenes. In this paper, the bifunctionalization of various alkenes in recent 12 years is reviewed. It can be divided into three parts:copper-catalyzed difunctionalization of alkenes, other transition metal-catalyzed difunctionalization of alkenes, and non-metal-catalyzed difunctionalization of alkenes. The prospects of this reaction are also discussed.

Key words: alkene, bifunctionalization, catalysis