Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (11): 3802-3811.DOI: 10.6023/cjoc202004040 Previous Articles     Next Articles


张依, 刘育   

  1. 南开大学化学系 元素有机化学国家重点实验室 天津 300071
  • 收稿日期:2020-04-25 修回日期:2020-04-29 发布日期:2020-05-11
  • 通讯作者: 刘育
  • 基金资助:

Supramolecular Assemblies of Multi-Charged Cyclodextrins

Zhang Yi, Liu Yu   

  1. State Key Laboratory of Elemento-organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071
  • Received:2020-04-25 Revised:2020-04-29 Published:2020-05-11
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21772099, 21861132001).

As a class of macrocyclic host with excellent water solubility, low biotoxicity and high charge density, multi-charged cyclodextrins have been extensively studied because they can interact with organic/inorganic/biological molecules through multiple synergistic forces such as the hydrophobic cavities and electrostatic interactions to construct the smart supramolecular assemblies with stable topology, functional diversity and stimulus responsiveness. The latest research progress of pH-, photo-, enzyme-, redox-, magnetic-and multi-stimulus responsive smart supramolecular assemblies, which are constructed by typical positively/negatively charged and amphiphilic multi-charged cyclodextrins including their application in the fields of drug delivery, controlled release and sensory detection is introduced, and the challenges and future developments of multi-charged cyclodextrin smart supramolecular assemblies are discussed.

Key words: multi-charged cyclodextrin, supramolecular assembly, stimulus responsiveness, smart material