Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (6): 2354-2360.DOI: 10.6023/cjoc202101017 Previous Articles     Next Articles


电化学介导的S—N键形成: 次磺酰胺化合物的简洁合成

何慕雪, 程诗砚, 潘永周, 唐海涛*(), 潘英明*()   

  1. 广西师范大学化学与药学学院 药物资源化学与分子工程国家重点实验室 广西桂林 541004
  • 收稿日期:2021-01-11 修回日期:2021-03-04 发布日期:2021-03-22
  • 通讯作者: 唐海涛, 潘英明
  • 基金资助:

Electrochemically Mediated S—N Bond Formation: Synthesis of Sulfenamides

Muxue He, Shiyan Cheng, Yongzhou Pan, Haitao Tang(), Yingming Pan()   

  1. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, Guangxi 541004
  • Received:2021-01-11 Revised:2021-03-04 Published:2021-03-22
  • Contact: Haitao Tang, Yingming Pan
  • Supported by:
    National Natural Science Foundation of China(22061003)

A series of sulfenamide compounds are synthesized by electrooxidation of thiophenols and amines. The electrosynthesis reaction does not require metal catalysts and oxidizing reagents, and uses simple devices such as single- chamber electrolyzers and constant current electrolysis. This method featured broad substrate scope, ready availability of starting materials, operational simplicity and environmental friendly, which provides a new strategy for the simple and convenient synthesis of various sulfenamide derivatives.

Key words: sulfenamides, organic electrosynthesis, S—N bond formation, dehydrogenative coupling