Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (7): 2810-2819.DOI: 10.6023/cjoc202102037 Previous Articles     Next Articles



祝改革, 赖晓辉, 王思雨, 林彩霞*(), 袁耀锋*()   

  1. 福州大学化学学院 福州 350108
  • 收稿日期:2021-02-21 修回日期:2021-03-23 发布日期:2021-04-12
  • 通讯作者: 林彩霞, 袁耀锋
  • 基金资助:
    国家自然科学基金(21772023); 国家自然科学基金(22071025)

Synthesis of 2-Imino-1,2-dihydroquinolines via Copper Catalysis

Gaige Zhu, Xiaohui Lai, Siyu Wang, Caixia Lin(), Yaofeng Yuan()   

  1. College of Chemistry, Fuzhou University, Fuzhou 350108
  • Received:2021-02-21 Revised:2021-03-23 Published:2021-04-12
  • Contact: Caixia Lin, Yaofeng Yuan
  • Supported by:
    National Natural Science Foundation of China(21772023); National Natural Science Foundation of China(22071025)

A mild three-component method for the synthesis of 2-imino-1,2-dihydroquinoline compounds has been successfully developed. In the presence of CuCl, various terminal alkynes, sulfonyl azides and 2-aminobenzaldehydes were coupled. When changing the type of substrate alkyne, controlled synthesis of dihydroquinoline and sulfonyl amidine compounds were achieved.

Key words: 2-imino-1, 2-dihydroquinoline, three-component synthesis, sulfonyl azides, alkynes