Chinese Journal of Organic Chemistry ›› 2022, Vol. 42 ›› Issue (4): 1002-1012.DOI: 10.6023/cjoc202109038 Previous Articles     Next Articles


单质硫: 合成含硫杂环的优质硫源

肖立伟*(), 刘光仙, 任萍, 吴彤桐, 卢玉伟, 孔洁   

  1. 廊坊师范学院化学与材料科学学院 河北廊坊 065000
  • 收稿日期:2021-09-24 发布日期:2021-12-08
  • 通讯作者: 肖立伟
  • 基金资助:
    河北省高等学校科学技术研究(ZD2020153); 河北省省属高等学校基本科研业务费研究(XKF202102); 大中学生科技创新能力培育专项(2021H100403)

Elemental Sulfur: An Excellent Sulfur-Source for Synthesis of Sulfur-Containing Heterocyclics

Liwei Xiao(), Guangxian Liu, Ping Ren, Tongtong Wu, Yuwei Lu, Jie Kong   

  1. College of Chemistry and Material Science, Langfang Normal University, Langfang, Hebei 065000
  • Received:2021-09-24 Published:2021-12-08
  • Contact: Liwei Xiao
  • Supported by:
    Science and Technology Project of Hebei Education Department(ZD2020153); Fundamental Research Funds for the Universities in Hebei Province(XKF202102); Special Project of Cultivating College Students Scientific and Technological Innovation Ability(2021H100403)

Sulfur-containing heterocyclic compounds are widely applied in many areas such as drugs, molecular devices and materials, etc., so their synthesis methods have attracted much attention. The key step for the synthesis of sulfur-containing heterocycles is the construction of C—S bond, which is generally realized by C—H bond functionalization or C—X bond coupling reaction with sulfur-containing organic or inorganic substances. Elemental sulfur is cheap, available and stable, and it is an excellent sulfur atom donor for the synthesis of sulfur-containing heterocycles. Therefore, the synthesis of sulfur-containing heterocycles from elemental sulfur has become a research hotspot. Herein, the recent research progress of synthesis of sulfur-containing heterocyclic employing sulfur as sulfur-source is reviewed.

Key words: sulfur-containing heterocycle, elemental sulfur, C—S bond construction, multi-component cascade reaction