Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (10): 1434-1436. Previous Articles     Next Articles




  1. (深圳大学师范学院化学系 深圳 518060)
  • 收稿日期:2006-02-06 修回日期:2006-06-09 发布日期:2006-09-19
  • 通讯作者: 高原

One-Pot Synthesis of 2-Amino-7-methyl-5-oxo-4-aryl-4H,5H-pyrano-[4,3-b]pyran-3-carbonitrile under Microwave Irradition

ZHANG Xue-Li,HUANG Yi,LI Zhuo-Ning,LÜ Yu-Juan,GAO Yuan*   

  1. (Department of Chemstry, Normal College, Shenzhen University, Shenzhen 518060)
  • Received:2006-02-06 Revised:2006-06-09 Published:2006-09-19
  • Contact: GAO Yuan

A series of 2-amino-7-methyl-5-oxo-4-aryl-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile were synthesized by one-pot reaction of aromatic aldehydes, malononitrile with 4-hydroxyl-6-methyl-2-pyranone under microwave irradiation. The structures of the products were confirmed by IR, 1H NMR, elemental analysis and X-ray analysis for 4g. A possible mechanism for this reaction was proposed.

Key words: malononitrile, 4-hydroxyl-6-methyl-2-pyranone, microwave, aromatic aldehyde