Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (12): 1631-1639. Previous Articles     Next Articles




  1. (山东大学微生物技术国家重点实验室 济南 250100)
  • 收稿日期:2006-01-15 修回日期:2006-03-10 发布日期:2006-11-21
  • 通讯作者: 肖敏

1-Glycosyl Fluorides in Carbohydrate Synthesis by Chemoenzymatic Methods

LU Li-Li,XIAO Min* , ZHAO Han,WANG Peng,QIAN Xin-Min   

  1. (State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100)
  • Received:2006-01-15 Revised:2006-03-10 Published:2006-11-21
  • Contact: XIAO Min

Chemoenzymatic methods have advantages over classical chemical methods in carbohydrate synthesis owing to stereoselectivity and regioselectivity. 1-Glycosyl fluorides, which act as glycosyl donors, are becoming increasingly important in the chemoenzymatic reactions. The application of 1-glycosyl fluorides in the glycosyl transferase and glycosidase-catalysed carbohydrate synthesis is reviewed in this paper.

Key words: chemoenzymatic synthesis, 1-glycosyl fluoride, carbohydrate, glycosidase, glycosyl transferase