Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (12): 1640-1646. Previous Articles     Next Articles




  1. (清华大学化学系 生命有机磷与化学生物学教育部重点实验室 北京 100084)
  • 收稿日期:2005-09-14 修回日期:2006-04-08 发布日期:2006-11-21
  • 通讯作者: 巨勇

Application of Azoles Synthesis in Bioconjugate Chemistry

LI Yan,JU Yong*,ZHAO Yu-Fen   

  1. (Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Ministry of Education,
    Department of Chemistry, Tsinghua University, Beijing 100084)
  • Received:2005-09-14 Revised:2006-04-08 Published:2006-11-21
  • Contact: JU Yong

The characterization of “Click Chemistry” (the 1,3-dipolar cycloaddition combined with the synthetic design of triazoles and tetrazoles) is reviewed, and some recent examples of various bioconjugates synthesis are introduced based on the “Click Chemistry”.

Key words: bioconjugate chemistry, azole, 1,3-dipolar cycloaddition