Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (11): 1444-1447. Previous Articles     Next Articles




  1. (a华中师范大学化学学院 武汉 430079)
    (b广州中医药大学中药学院 广州 510405)
  • 收稿日期:2006-10-09 修回日期:2007-05-08 发布日期:2007-10-20
  • 通讯作者: 汪焱钢

Synthesis and Biological Activity of N-(5-Mercapto-1,3,4-thiadiazol-2- yl)-N'-(un)substituted Benzoylureas and (Un)substituted Phenoxyacetylureas

CHEN Chuan-Binga,b,ZHANG Zheng-Wena,DU Mina
WANG Shenga,WANG Yan-Gang*,a   

  1. (a College of Chemistry, Central China Normal University, Wuhan 430079)
    (b College of Traditional Chinese Medicine, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405)
  • Received:2006-10-09 Revised:2007-05-08 Published:2007-10-20
  • Contact: WANG Yan-Gang

Twenty-one new (un)substituted benzoylureas and (un)substituted phenoxyacetylureas have been synthesized by the reaction of 2-amino-5-mercapto-1,3,4-thiadiazole with (un)substituted benzoyl isocy-anates and (un)substituted phenoxyacetyl isocyanates, respectively, and their structures were confirmed by IR, 1H NMR spectra and elemental analysis. The preliminary biological activity tests showed that some of the title compounds had good activity as plant growth regulators.

Key words: (un)substituted phenoxyacetylurea, 1,3,4-thiadiazole, biological activity, synthesis, (us)subsitituted benzoylurea