Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (08): 1348-1357. Previous Articles     Next Articles



刘文剑; 肖玉梅*; 傅 滨; 李 楠 ; 覃兆海*   

  1. (中国农业大学应用化学系 北京 100094)
  • 收稿日期:2007-07-01 修回日期:2007-10-15 发布日期:2008-08-18
  • 通讯作者: 肖玉梅*; 覃兆海*

Progress in Asymmetrically Catalyzed Addition of Organozinc Reagents to Ketones

LIU, Wen-Jian; XIAO, Yu-Mei*; FU, Bin; LI, Nan ; QIN, Zhao-Hai*   

  1. (Department of Science, China Agricultural University, Beijing 100094)
  • Received:2007-07-01 Revised:2007-10-15 Published:2008-08-18

The recent advancement of the asymmetric addition of organozinc reagents to ketones and α-ketoesters is reviewed according to the type of the chiral ligands, with an emphasis on the introduction of the ligands with high efficiency and high selectivity.

Key words: organozinc reagent, α-ketoester, asymmetric addition, enantioselectivity, ketone