Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (08): 1467-1470. Previous Articles     Next Articles



张圣领*,a ; 黄志纾b ; 古练权b   

  1. (a韶关学院化学系 韶关 512005)
    (b中山大学药学院 广州 510275)
  • 收稿日期:2007-10-18 修回日期:2008-01-25 发布日期:2008-08-18
  • 通讯作者: 张圣领

Synthesis of 2,3-Disubstituted-1,4-naphthoquinone by Michael Addition of 4-Hydroxycoumarins to 1,4-Naphthoquinone

ZHANG, Sheng-Ling*,a ; HUANG, Zhi-Shub ; GU, Lian-Quanb   

  1. (a Department of Chemistry, Shaoguan College, Shaoguan 512005)
    (b School of Pharmaceutical Science, Zhongshan University, Guangzhou 510275)
  • Received:2007-10-18 Revised:2008-01-25 Published:2008-08-18
  • Contact: ZHANG, Sheng-Ling

Six 2,3-disubstituted-1,4-naphthoquinones were synthesized by the Michael addition of 4-hydroxycoumarins to 1,4-naphthoquinone in aqueous acetone (V∶V=1∶1) at room temperature. The structures of these compounds were determined by MS, 1H NMR spectra and elemental analysis.