Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (09): 1534-1544. Previous Articles     Next Articles

Review

黄酮类化合物生理活性及合成研究进展

延 玺* ; 刘会青; 邹永青; 任占华   

  1. 北京师范大学化学学院 北京 100875
  • 收稿日期:2007-11-27 修回日期:2008-01-22 出版日期:2008-09-20 发布日期:2008-09-20
  • 通讯作者: 延 玺

Physiological Activities and Research Advance in Synthesis of Flavonoids

YAN, Xi*; LIU, Hui-Qing; ZOU, Yong-Qing; REN, Zhan-Hua   

  1. College of Chemistry, Beijing Normal University, Beijing 100875
  • Received:2007-11-27 Revised:2008-01-22 Online:2008-09-20 Published:2008-09-20
  • Contact: YAN, Xi

Flavonoids are a kind of secondary metabolite of plants, which are widely distributed in almost all plants owing to huge diversity in the category and configuration. Flavonoids, with unique chemical structures, are bearing many important physiological and biochemical effects on mammals and other types of cells. Adequate intakes of flavonoids are reported to be associated with reduced risks of cancer, tumor, car-diovascular disease, lipid peroxidation and osteoporosis. With increasing research of the structure-activity relationship, functionary mechanism of partial pharmacological actions is discovered. This progress provides a theoretical basis of flavonoids for their application to medicine and food industry, and certainly accelerates their development. In this essay, the physiological activities and research advance in synthesis of flavonoids are summarized.

Key words: flavonoid, physiological activity, synthesis, drug