Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (09): 1566-1571.
金蔚蔚; 吴文彦; 张 倩*; 夏 鹏
JIN, Wei-Wei ; WU, Wen-Yan ; ZHANG, Qian* ; XIA, Peng
Some different demethylation products and the double bond isomer of 2-bromo-4-[1-eth-(E)- ylidene-2-(4-methoxy-phenyl)-butyl]-1-methoxy-benzene (3) were obtained under different conditions dur-ing synthesizing 3’-methoxyl-1,2-diethystilbestrol (2). The angiogenesis inhibitory activities of some com-pounds were evaluated on human umbilical vein endothelial cells and the assay data indicated that the groups substituted on the skeleton of diethystilbestrol analogs could significantly affect their anti-angiogenesis activities.
isomerisation of double bond reaction,
JIN, Wei-Wei ; WU, Wen-Yan ; ZHANG, Qian* ; XIA, Peng. Demethylation and Double-Bond Isomerisation of 2-Bromo-4-[1-eth- (E)-ylidene-2-(4-methoxy-phenyl)-butyl]-1-methoxy-benzene[J]. Chin. J. Org. Chem., 2008, 28(09): 1566-1571.
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