Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (09): 1633-1636. Previous Articles     Next Articles

Reports

水介质中吡喃并[3,2-c]吡喃-5-酮衍生物的三组分一锅合成

史达清*,a,b; 牛力惠b ; 庄启亚b   

  1. (a苏州大学化学化工学院 苏州 215123)
    (b徐州师范大学化学化工学院 徐州 221116)
  • 收稿日期:2008-02-27 修回日期:2008-03-26 发布日期:2008-09-20
  • 通讯作者: 史达清

Synthesis of Pyrano[3,2-c]pyran-5-one Derivatives by Three- Component One-Pot Reaction in Aqueous Media

SHI, Da-Qing*,a,b; NIU, Li-Huib ; ZHUANG, Qi-Yab   

  1. (a College of Chemistry and Chemical Engineering, Suzhou University, Suzhou 215123)
    (b College of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou 221116)
  • Received:2008-02-27 Revised:2008-03-26 Published:2008-09-20
  • Contact: SHI, Da-Qing

A series of 2-amino-3-cyano-4-aryl-4H,5H-pyrano[3,2-c]pyran-5-one was synthesized by a three-component reaction of aromatic aldehydes, malononitrile and 4-hydroxy-6-methylpyran-2-one using triethylbenzylammonium chloride as catalyst in aqueous media. This method has some advantages of good yields, less pollution, simple operation and environmental friendliness.

Key words: pyrano[3,2-c]pyran-5-one, three-component, aqueous media, one-pot synthesis